Dierickx CC, Mazer JM, Sand M, Koenig S, Arigon V. Safety, Tolerance, and Patient Satisfaction with Noninvasive Cryolipolysis.
Dermatol Surg. 2013 Aug;39(8):1209-16.
Key Points:

• 86% of patients showed visible improvement to the treated area.
• 82% of patients would recommend the procedure to others.

Effectiveness is visually supported by photographic evidence.

Dover, MD, J. Burns, MD, S. Coleman, MD, R. Fitzpatrick, MD, J. Garden, MD, D. Goldberg, MD, R. Geronemus, MD, S. Kilmer, MD, F. Mayoral, MD, E. Tanzi, MD, R. Weiss, MD, and B. Zelickson, MD
Key Points:

• Visible Improvement, and Effectiveness are demonstrated and supported with photographic evidence as well as ultrasound evidence.
• Cryolipolysis results in reductions in subcutaneous fat volume without damage to the surrounding tissues.

Explicitly states that Cryolipolysis results in cold-induced apoptotic fat cell death.

Manstein D, Laubach H, Watanabe K, Farinelli W, Zurakowski D, Anderson RR. Selective Cryolipolysis: A Novel Method of Non-Invasive Fat Removal. Lasers in Surgery and Medicine. 2008; 40:595-604.

Klein K, Zelickson B, Riopelle JG, Okamoto E, Bachelor EP, Harry RS, Preciado JA. Non-Invasive Cryolipolysis for Subcutaneous Fat Reduction Does Not Affect Serum Lipid Levels or Liver Function Tests. Lasers in Surgery and Medicine. 2009; 41(10):785-790.

Coleman SR, Sachdeva K, Egbert BM, Preciado J, Allison J. Clinical Efficacy of Noninvasive Cryolipolysis and Its Effects on Peripheral Nerves. Aesthetic Plastic Surgery. 2009; 33(4):482-488.

Bernstein EF, Long-term efficacy follow-up on two cryolipolysis case studies: 6 and 9 years post-treatment. Journal of Cosmetic Dermatology. 2016. Early View (online version of record published before inclusion in an issue)